he Role of Glycated Hemoglobin in the Diagnosis and Monitoring of Diabetes Mellitus

L.А. Lutsenko

Abstract


Considering the prevalence of diabetes mellitus, the possibility of early and rapid progression of its complications, a large number of undiagnosed cases and disappointing prognosis of the World Health Organization on the prospects of diabetes mellitus spreading in the world, timely and accurate diagnosis of carbohydrate metabolism disorders is important. The glycated hemoglobin is an indicator that, while using the standardized methods, provides an integrated view of the glycemia level during a long period of time and helps to detect timely the carbohydrate metabolism disorders. While using the glycated hemoglobin as a diagnostic criterion of carbohydrate metabolism disorders or degree of diabetes mellitus compensation, the correct approach to the choice of the method of this index determination, considering its analytical reliability, is important.

Keywords


diabetes mellitus; glycated hemoglobin; glycation; glycemic control

References


International Diabetes Federation, diabetes alas. — 6th ed. // International Diabetes Federation. — 2013. — 159 р.

Gonen B.A. Hemoglobin A1: An indicator of the metabolic control of diabetic patients / B.A. Gonen, A.H. Rubinstein, H. Rochman et al. // The Lancet. — 1977. — Vol. 310. — Р. 734-737.

Koenig R.J. Correlation of glucose regulation and hemoglobin A1c in diabetes mellitus / R.J. Koenig, C.M. Peterson, R.L. Jones et al. // New England Journal of Medicine. — 1976. — Vol. 295, № 8. — Р. 417-420.

Королев В.А. Метод изоэлектрофокусирования и фотоколориметрия для определения гемоглобина A1с / В.А. Королев, В.И. Молчанов // Биомедицинская химия. — 2006. — Т. 52, № 2. — С. 200-210.

Питерс-Хармел Э. Сахарный диабет: диагностика и лечение / Э. Питерс-Хармел, Р. Матур: Пер. с англ. — М.: Практика, 2008. — 496 с.

American Diabetes Association Standards of Medical Care in Diabetes — 2010 // Diabetes Care. — 2010. — Vol. 33(1). — P. 511-561.

International expert committee report on the role of the A1c assay in the diagnosis of diabetes // Diabetes Care. — 2009. — Vol. 32(7). — P. 1327-1334.

Approved IFCC reference method for the measurement of HbA1c in human blood // Clin. Chem. Lab. Med. — 2002. — Vol. 40(1). — Р. 78-89.

DCCT. The relationship of glycemic exposure (HbA1c ) to the risk of development and progression of retinopathy in the diabetes control and complications trial // Diabetes. — 1995. — Vol. 44(8). — P. 968-983.

Stratton J.M. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective, observational study / J.M. Stratton, A.I. Adler, A.W. Neil et al. // BMJ. — 2000. — Vol. 321. — Р. 405-412.

Гнуди Л. Результаты и влияние исследований ACCORD и ADVANCE / Л. Гнуди // Diabetes voice. — 2009. — Vol. 54, № 1. — С. 29-32.




DOI: https://doi.org/10.22141/2307-1257.0.4.10.2014.76041

Refbacks

  • There are currently no refbacks.


Copyright (c) 2016 KIDNEYS

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© "Publishing House "Zaslavsky", 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru